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Newest / Plinest
Biostimulator & Regenerative

Polynucleotides (PN/PDRN).

Newest / Plinest

Newest / Plinest
What is Newest / Plinest?

A regenerative injectable that rebuilds skin quality from within.

Newest and Plinest are polynucleotide injectables: a regenerative treatment that works beneath the surface rather than filling it. Purified polynucleotides stimulate the fibroblasts responsible for collagen and elastin, improving hydration, elasticity and overall skin quality over time. This is a repair, not a volumiser.

At DROM, we use polynucleotides to reach what skincare cannot: fine, crepey texture, dull tone and tired under-eye skin. Each treatment is mapped to your skin, with the programme and number of sessions agreed in consultation before we begin.

What We Use

Polynucleotides (PN/PDRN).

Newest and Plinest are highly purified polynucleotide injectables, in the same regenerative family as Rejuran. The active is derived from purified fish DNA fragments that signal the skin to repair and remodel itself. The brand and formulation are chosen in consultation, based on the area treated and your skin goals.

Benefits

Why patients choose this

A treatment that improves the quality of the skin itself, not merely its surface.

Stimulates collagen

Activates fibroblasts to rebuild collagen and elastin from within the dermis.

Improves elasticity

Skin feels firmer and more resilient as its structure is restored.

Deep hydration

Draws and holds moisture in the dermis for a smoother, plumper finish.

Under-eye renewal

Well suited to thin, crepey under-eye skin, where filler is not appropriate.

Natural results

Improves the skin you have, rather than adding volume or altering your features.

Minimal downtime

Most people return to normal activity the same day, and pinpoint marks settle quickly.

Suits delicate areas

Suitable, after assessment, for fine, lax or sensitive skin on the face, neck and around the eyes.

Builds over time

Results develop and deepen with each session as the skin regenerates.

Process

How the treatment works

Six steps, from consultation to a gradual, building result.

Consultation

We assess your skin quality, concerns and goals in person, and agree a plan.

Cleansing

The treatment area is thoroughly cleansed to remove any impurities.

Numbing

A topical anaesthetic is applied and left to take effect for your comfort.

Injection

Polynucleotides are delivered into the dermis with a fine needle. You may feel a brief pinch.

Aftercare

We provide written aftercare guidance and direct contact before you leave.

Onset of effect

Hydration improves within two to three weeks, and firmness builds over several weeks.

Expected Results

What the result looks like.

  • Improved hydration and a plumper, smoother surface within two to three weeks.
  • Better skin texture, tone and brightness as collagen rebuilds.
  • Firmer, more elastic skin developing over several weeks.
  • Fresher, less tired under-eye skin where treated.
  • A course of two to three sessions is usually advised, with results lasting around six to nine months.
Aftercare & Recovery

The first 48 hours.

  • Avoid make-up on the treated area for 24 hours.
  • Avoid strenuous exercise, saunas and steam rooms for 48 hours.
  • Avoid alcohol for 24 hours to reduce the risk of bruising.
  • Skip active skincare such as retinoids and acids for 48 hours, and apply a daily SPF.
  • Mild redness, swelling or small bumps may appear at the injection sites. These settle within 24 to 48 hours.
Next step

Considering Newest / Plinest?

Book an in-person consultation. We'll assess your anatomy and discuss whether Newest / Plinest, alone or in combination, fits your goals.

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The DROM Clinic reception, with a marble desk, staircase and neon sign
Get in Touch

Begin with a consultation, not a treatment.

Book

By appointment only

Email

hello@dromclinic.com

WhatsApp

+44 7351 842001

Come and visit us

81-83 Walton Street, London SW3 2HP